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CD46 — IL6

Text-mined interactions from Literome

Viedt et al., J Am Soc Nephrol 2002 (Nephritis) : In parallel, MCP-1 increased IL-6 and ICAM-1 mRNA expression in human TECs
Marie et al., Nat Immunol 2002 (Dermatitis, Contact...) : We found that engagement of CD46-1 or CD46-2 differentially affected CD8 ( + ) T cell cytotoxicity, CD4 ( + ) T cell proliferation, interleukin 2 (IL-2) and IL-10 production as well as tyrosine phosphorylation of Vav in T lymphocytes
Rott et al., Atherosclerosis 2003 (Arteriosclerosis...) : IL-6 induced , in a dose response fashion, MCP-1 expression in human ECs : 0, 2, 10, and 50 pg/ml IL-6 increased MCP-1 levels in EC conditioned medium from 1120+/-65 to 1148+/-105, 1395+/-40, and 2119+/-130 pg/ml, respectively ( P < 0.001 )
Yamamoto et al., Toxicol Appl Pharmacol 2006 (Pneumonia) : LTA produced a dose related increase in early pulmonary inflammation, which was characterized by ( 1 ) influx of polymorphonuclear neutrophils ( PMNs ) and ( 2 ) induction of interleukin (IL)-6 , tumor necrosis factor (TNF)-alpha, macrophage inflammatory protein (MIP)-1alpha/CCL3, but no effect on monocyte chemoattractant protein (MCP)-1/CCL2 at 24 h after instillation
Chen et al., Br J Pharmacol 2006 : Furthermore, Mag suppressed IL-6 induced promoter activity of cyclin D1 and monocyte chemotactic protein (MCP)-1 for which STAT3 activation plays a role
Alexander et al., Brain Behav Immun 2007 (Amyotrophic Lateral Sclerosis...) : The most common pattern was found in 50 % ( 11 out of 22 ) of the CRPS patients and consisted of ; elevated IL-6 , low levels of IL-4 or IL-10, increased GFAP or MCP1 and increases in at least two of the following markers NO metabolites, calcium or glutamate
Buettner et al., Mol Cancer Res 2007 (Breast Neoplasms...) : CD46 mRNA expression is induced by interleukin-6 and by transient transfection of normal human epithelial cells with a persistently active mutant construct of STAT3, STAT3C
Wang et al., Arterioscler Thromb 1991 : Tumor necrosis factor and bacterial lipopolysaccharide but not IL-6 also induced MCP and IL-8 gene expression in SMCs. Nuclear runoff analysis revealed that IL-1 augmented transcription of the MCP and IL-8 genes
Jones et al., J Immunol 2009 : Neither the genetic absence of IL-4, IL-4Ralpha chain, STAT-6, IFN-gamma, or IL-12p40 nor mAb blockade of IFN-gamma, IL-3, IL-4, IL-5, IL-6 , IL-10, IL-13, IL-17A, IL-12p40, or IL-12p40Rbeta1 before Ag challenge in WT mice reduces the pulmonary MCp increase
Bayraktar et al., Am J Reprod Immunol 2009 : IL-6 and IL-8 were induced to comparable levels in response to both LTA and LPS whereas monocyte chemotactic protein-1 (MCP-1) production was induced more by LTA, demonstrating a differential placental response to a specific toll-like receptor ( TLR ) ligand
Jougasaki et al., Br J Pharmacol 2010 : We investigated the effects of statins on interleukin (IL)-6 induced monocyte chemo-attractant protein (MCP)-1 expression and monocyte chemotaxis
Timper et al., Am J Physiol Endocrinol Metab 2013 (Insulin Resistance) : GIP induced mRNA expression of IL-6 , IL-1ß, and the IL-1 receptor antagonist IL-1Ra, whereas TNFa, IL-8, and monocyte chemotactic protein (MCP)-1 remained unchanged
Kim et al., Mol Med Report 2013 : Monocyte chemotactic protein-1 (MCP-1)/CCL2 , interleukin (IL)-6 and IL-8 increased following DpE treatment and arazyme significantly blocked the increase of MCP-1, IL-6 and IL-8 expression in cell types
Strieter et al., Biochem Biophys Res Commun 1989 : In addition, neither primary cultures expressed MCP in response to interleukin-6
Sironi et al., Eur J Immunol 1993 : In addition to IL-6, murine IL-10 induced or amplified expression of the chemoattractant cytokines monocyte chemotactic protein-1 (MCP-1) and KC. Human IL-10 inhibited IL-6 release by LPS stimulated human peripheral blood mononuclear cells, whereas it did not interfere with cytokine production by LPS- or IL-1 stimulated human umbilical vein endothelial cells
Biswas et al., Blood 1998 (HIV Infections...) : In the present study, we show that the proinflammatory cytokine interleukin-6 (IL-6) potently induced mRNA expression and secretion of the CC chemokine monocyte chemotactic protein 1 (MCP-1) in PBMCs
Huang et al., J Immunol 1998 (Peritonitis) : Mouse MCP-6 did not induce cultured human endothelial cells to express TNF-alpha, RANTES, IL-1alpha, or IL-6