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IL18 — NOX1

Text-mined interactions from Literome

Tojo et al., J Hypertens 2005 (Hypertension, Renal) : Nicotinamide adenine dinucleotide phosphate ( NAD ( P ) H ) oxidase is regulated by angiotensin II, interleukin (IL)-1beta and tumor necrosis factor (TNF)-alpha via p38 mitogen activated protein kinase ( MAPK )
Valente et al., Am J Physiol Heart Circ Physiol 2012 (Hyperplasia) : Similar to ANG II, addition of IL-18 also induced superoxide generation, activated NF-?B and AP-1, and stimulated SMC migration and proliferation, in part via Nox1, and both ANG II and IL-18 induced NOX1 transcription in an AP-1 dependent manner ... Interestingly, exogenous IL-18 neither induced AT(1) binding to Nox1 nor enhanced the ANG II-induced increase in AT(1)/Nox1 binding
Valente et al., Cell Signal 2013 : Interleukin-18 enhances IL-18R/Nox1 binding, and mediates TRAF3IP2 dependent smooth muscle cell migration