Gene interactions and pathways from curated databases and text-mining

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GZMB — IL18

Text-mined interactions from Literome

Marshall et al., J Immunol 2010 (Arenaviridae Infections) : IL-12, IL-15, IL-18 , and IFN-gamma were not individually required for sensitization to produce IFN-gamma, but IL-15 was required for upregulation of granzyme B
Hwang et al., PloS one 2012 (Influenza, Human) : Analysis of cytokine receptor deficient mice demonstrated that type I interferons ( IFNs ), but not IL-12 or IL-18 , were critical for the NK cell expression of both IFN-? and granzyme B in response to flu infection