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IL15 — SHC1
Text-mined interactions from Literome
de Totero et al., Blood 2008
(Leukemia, Lymphocytic, Chronic, B-Cell...) :
Moreover,
IL-15 but not IL-21
caused an increased phosphorylation of
Shc and ERK1/2
Matsuguchi et al., J Biol Chem 1994
(Leukemia, Megakaryoblastic, Acute) :
Shc phosphorylation in myeloid cells is
regulated by granulocyte macrophage colony stimulating factor,
interleukin-3 , and steel factor and is constitutively increased by p210BCR/ABL
Barber et al., Blood 1997
:
Although stimulation with IL-2 or
IL-15 resulted in the rapid, dose dependent tyrosine phosphorylation of
Shc , stimulation with EPO failed to activate Shc