Gene interactions and pathways from curated databases and text-mining

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IL15 — SHC1

Text-mined interactions from Literome

de Totero et al., Blood 2008 (Leukemia, Lymphocytic, Chronic, B-Cell...) : Moreover, IL-15 but not IL-21 caused an increased phosphorylation of Shc and ERK1/2
Matsuguchi et al., J Biol Chem 1994 (Leukemia, Megakaryoblastic, Acute) : Shc phosphorylation in myeloid cells is regulated by granulocyte macrophage colony stimulating factor, interleukin-3 , and steel factor and is constitutively increased by p210BCR/ABL
Barber et al., Blood 1997 : Although stimulation with IL-2 or IL-15 resulted in the rapid, dose dependent tyrosine phosphorylation of Shc , stimulation with EPO failed to activate Shc