Gene interactions and pathways from curated databases and text-mining

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E2F6 — E2F7

Text-mined interactions from Literome

Di Stefano et al., EMBO J 2003 : Interestingly, however, E2F7 binds only a subset of E2F dependent promoters in vivo, and in agreement with this, inhibition of E2F7 expression results in specific derepression of these promoters
Wong et al., Biochem Biophys Res Commun 2004 (Carcinoma, Squamous Cell) : Significantly, although E2F6 could suppress E2F activity in proliferating cells, it could not inhibit proliferation of KJD-1/SV40 cells
Yang et al., Mol Biol Cell 2008 (Anoxia) : Interestingly, E2F1 transactivation and apoptosis induced by hypoxia in cells stably expressing E2F1 were inhibited by E2F6 overexpression, suggesting that the inhibitory effects of E2F6 are not only mediated by the repression of E2F1 promoter
Leung et al., PloS one 2012 : We have previously provided evidence suggesting a role for E2F6 in repression of E2F-responsive genes at S phase