Gene interactions and pathways from curated databases and text-mining

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CAPN13 — CAPN2

Text-mined interactions from Literome

Satish et al., Mol Cell Biol 2005 : Molecular downregulation or RNA interference mediated depletion of mu-calpain ( calpain 1 ) but not M-calpain ( calpain 2 ) blocked IP-9 induced calpain activation and motility
Lee et al., J Biol Chem 2005 : We found that calpain activity increased in response to RANKL in both cell types based on alpha-spectrinolysis and that mu-calpain, rather than m-calpain , was activated during RANKL supported osteoclastogenesis in RAW 264.7 cells
Dutt et al., BMC developmental biology 2006 : Disruption of the Capn1 gene produced viable, fertile mice implying that either m-calpain could compensate for the loss of mu-calpain , or that the loss of m-calpain was responsible for death of Capn4-/- mice
Saito et al., Comp Biochem Physiol B Biochem Mol Biol 2007 : Trout mu-calpain requires 4.4+/-2.8 microM and trout m-calpain requires 585+/-51 microM Ca ( 2+ ) for half-maximal activity, similar to the Ca ( 2+ ) requirements of mu- and m-calpain from mammalian tissues
Li et al., Neurochem Int 1995 (Spinal Cord Injuries) : Role of calpain in spinal cord injury : increased mcalpain immunoreactivity in spinal cord after compression injury in the rat
Neuberger et al., J Neurosci Res 1997 : In contrast, both acidic FGF and basic FGF stimulated mu calpain ( 37 % ) and mcalpain ( 58 % ) of tSC while PDGF-aa and PDGF-bb inhibited both calpain activities