Gene interactions and pathways from curated databases and text-mining

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BCL2 — IFI27

Text-mined interactions from Literome

Kim et al., Cancer Lett 2000 : These findings indicate that p27 ( kip1 ) may play important roles in mediating ceramide induced apoptosis and its expression can be regulated by Bax and Bcl-2
Fahy et al., J Surg Res 2003 (Adenocarcinoma...) : Bortezomib treatment led to accumulation of p21 ( WAF1/CIP1 ) and p27 ( KIP1 ) and decreased BCL-2 ; gemcitabine decreased p27 ( KIP1 ), induced BCL-2 and had no effect on p21 ( WAF1/CIP1 )
Festuccia et al., Endocr Relat Cancer 2009 (Disease Models, Animal...) : In vivo, azacitidine ( 0.8 mg/kg i.p. ) reduced tumor proliferation and induced apoptosis in both xenografts upmodulating the expression of p16INKA, Bax, Bak, p21/WAF1, and p27/KIP1 , and inhibiting the activation of Akt activity and the expression of cyclin D1, Bcl-2, and Bcl-XL ... In vivo, azacitidine ( 0.8 mg/kg i.p. ) reduced tumor proliferation and induced apoptosis in both xenografts upmodulating the expression of p16INKA, Bax, Bak, p21/WAF1, and p27/KIP1 , and inhibiting the activation of Akt activity and the expression of cyclin D1, Bcl-2 , and Bcl-XL
Chen et al., J Huazhong Univ Sci Technolog Med Sci 2010 (Carcinoma, Hepatocellular...) : Effects of Ad-p27mt gene transfer on the expression of Bax, Bcl-2 , VEGF and MMP-9 in the transplanted liver tumors in nude mice
Ganapathy et al., PloS one 2010 (Neoplasm Metastasis...) : In xenografted tumors, resveratrol upregulated the expressions of TRAIL-R1/DR4, TRAIL-R2/DR5, Bax and p27 ( /KIP1 ), and inhibited the expression of Bcl-2 and cyclin D1