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AR — PIAS1

Pathways - manually collected, often from reviews:

• OpenBEL Selventa BEL large corpus: AR → PIAS1 (increases, PIAS1 Activity)
  Evidence: In transient cotransfection assays using CV1 cells with full-length human AR and a mouse mammary tumor virus luciferase reporter vector, there was an androgen-dependent 3- to 5-fold greater increase in luciferase activity with PIAS1 over that obtained with an equal amount of control antisense cDNA or mutant PIAS1
• NCI Pathway Database Coregulation of Androgen receptor activity: PIAS1 (PIAS1) → AR/T-DHT complex (AR) (transcription, activates) Gross et al., Oncogene 2001*
  Evidence: reporter gene

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

• IRef Biogrid Interaction: PIAS1 — AR (direct interaction, two hybrid) Kotaja et al., Mol Endocrinol 2000
• IRef Hprd Interaction: AR — PIAS1 (in vitro) Tan et al., J Biol Chem 2002*, Nishida et al., J Biol Chem 2002*
• IRef Hprd Interaction: AR — PIAS1 (in vivo) Tan et al., J Biol Chem 2002*, Nishida et al., J Biol Chem 2002*