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CRK — PDGFB
Pathways - manually collected, often from reviews:
-
Reactome Reaction:
PDGFB
→
CRK
(indirect_complex)
Heldin et al., Physiol Rev 1999, Yokote et al., Oncogene 1998, Heldin et al., Biochim Biophys Acta 1998
-
Reactome Reaction:
PDGFB
→
CRK
(reaction)
Heldin et al., Physiol Rev 1999, Yokote et al., Oncogene 1998, Heldin et al., Biochim Biophys Acta 1998
Text-mined interactions from Literome
Romano et al., J Cell Physiol 2006
:
PI3K, ERK, JNK, and p38 kinases, known to mediate PDGF-BB signaling in the canonic dedifferentiative and proliferative response of smooth muscle cells ( SMC ) were rapidly activated by
PDGF-BB but only
p38 remained
activated after 2-day stimulation
Chiang et al., Life Sci 2007
(Melanoma) :
PDGF-BB induced phosphorylation of PDGF receptor beta ( PDGFR-beta ), extracellular signal regulated kinase 1/2 ( ERK1/2 ),
p38 , and c-Jun N-terminal kinase (JNK) was attenuated by lycopene in a concentration dependent manner, whereas the total expression of each protein was not affected