Gene interactions and pathways from curated databases and text-mining

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MAPK3 — RASGRP3

Text-mined interactions from Literome

Brodie et al., Mol Pharmacol 2004 : We found that overexpression of either PKCdelta or RasGRP3 increased the activation of Erk1/2 by PMA
Yang et al., Cancer Res 2010 (Prostatic Neoplasms) : Inhibition of RasGRP3 expression reduced AKT and extracellular signal regulated kinase 1/2 phosphorylation and sensitized the cells to killing by carboplatin
Ko et al., Translational research : the journal of laboratory and clinical medicine 2011 (MAP Kinase Signaling System) : Gene silencing of Ras-GRP1 prevented the PTH mediated suppression of NCC activity, the activation of the H-Ras isoform of Ras, and the activation of ERK1/2 MAPK