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IRF6 — PRDX5

Text-mined interactions from Literome

Ejima et al., Placenta 1999 : In this study, to investigate further the roles of thioredoxin and thioredoxin reductase in protecting pregnancy against oxidative stress, we examined the effect of lipopolysaccharide (LPS) , which induces a variety of cytokines and produces radical oxygen species, on the expression of thioredoxin and thioredoxin reductase in mouse placenta
Sun et al., J Neurochem 2010 : We demonstrate that microglial peroxiredoxin (Prx) 5 expression is up-regulated by lipopolysaccharide (LPS) through activation of the ROS-sensitive signaling pathway and is involved in attenuation of both microglial activation and nitric oxide ( NO ) generation ... Reduction of ROS level by treatment with either NADPH oxidase inhibitor or antioxidant ablates LPS mediated Prx V up-regulation in BV-2 microglial cells and is closely associated with the activation of the c-jun N-terminal kinase ( JNK ) signaling pathway ... This suggests the involvement of ROS/JNK signaling in LPS mediated Prx V induction