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IRF6 — NOD2
Text-mined interactions from Literome
Yang et al., J Immunol 2005
:
Induction of
Nod2 mRNA expression by
LPS but not by TNF-alpha in osteoblasts was dependent on TLR4 and MyD88
Yamashita et al., Nihon rinsho. Japanese journal of clinical medicine 2005
:
Osteoblasts express
NOD2 , an intracellular sensor for MDP, in
response to
LPS , IL-1 and TNF
Oh et al., Cell Immunol 2005
:
Human umbilical vascular endothelial cells ( HUVECs ) minimally expressed NOD2 gene, whereas stimulation of HUVEC with bacterial
LPS , IL-1beta, or TNF-alpha
resulted in significant up-regulation of
NOD2
Yamashita et al., Clinical calcium 2006
:
Osteoblasts express
nucleotide oligomerization domain (NOD)2 , an intracellular sensor for MDP, in
response to
LPS , IL-1 and TNF
Kim et al., J Immunol 2008
(MAP Kinase Signaling System...) :
These changes were accompanied by the suppression of the
LPS induced expression of TLR4,
NOD1 , and NOD2, and the induction of IRAK-M, with a concurrent reduction of TNF-alpha secretion ... These changes were accompanied by the suppression of the
LPS induced expression of TLR4, NOD1, and
NOD2 , and the induction of IRAK-M, with a concurrent reduction of TNF-alpha secretion
Mühlbauer et al., Immunology 2008
:
The
LPS and lipid A rapidly ( 1 hr )
induced Nod2 messenger RNA accumulation in a dose dependent manner ... Molecular blockade of nuclear factor-kappaB signalling with adenovirus 5 (Ad5) I kappaB AA or adenovirus 5 double negative (Ad5dn) IKK beta prevented
LPS induced
Nod2 gene expression
Farkas et al., Scand J Immunol 2008
:
We also demonstrate that
lipopolysaccharide (LPS) can further
increase NOD2 transcription in a TNF-alpha and IFN-gamma induced activation state
Mulla et al., Am J Reprod Immunol 2009
:
This study demonstrates that
LPS , through TLR4,
increases trophoblast expression of Nod1 and
Nod2 via the NFkappaB pathway ; and that Nod1 is functional in the trophoblast
Lappas et al., Biol Reprod 2013
:
The aims of this study were to determine the effect of 1 ) human labor, proinflammatory cytokines, and bacterial endotoxin
LPS on NOD1 and NOD2 expression and 2 ) NOD1 and
NOD2 activation on the expression of prolabor mediators in human fetal membranes and myometrium ... Furthermore,
LPS induced
NOD2 expression was decreased by the NFKB inhibitor BAY 11-7082