◀ Back to IRF6

IRF6 — NLRP3

Text-mined interactions from Literome

Schroder et al., Immunobiology 2012 : Previous work has attributed this phenomenon ( known as LPS ` priming ' ) to LPS dependent induction of NLRP3 expression
Liao et al., Inflamm Res 2013 : LPS induced NLRP3 protein expression was regulated through the NADPH oxidase/ROS/NF-?B dependent, JAK2/PI3-kinase/AKT/NF-?B dependent, and MAPK dependent pathways, while ATP induced caspase-1 activation was regulated through the NADPH oxidase/ROS dependent pathway
Hernandez-Cuellar et al., J Immunol 2012 : In this study, we found that endogenous NO is involved in the regulation of NLRP3 inflammasome activation by either IFN-ß pretreatment or long-term LPS stimulation
Pontillo et al., Reprod Sci 2013 : In CTBs and DSCs, LPS induced an augmented expression of CASP1 and IL1B and the specific upregulation of NLRP3 within the 3 NLRs tested
Mao et al., Drug Alcohol Depend 2013 : However, there was only a 2.7-fold increase in NLRP3 expression in response to LPS in the morphine-tolerant rats compared to a 4.5-fold increase in the placebo-control animals ... Our data indicate that, in the morphine-tolerant state, LPS induced expression of NLRP3 is suppressed and cytokine/chemokine expression is inhibited, which may be one of the mechanisms involved in morphine induced immunosuppression