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IKBKAP — IRF6

Text-mined interactions from Literome

Huang et al., J Biomed Sci 2003 : We found that LPS induced I kappa B kinase and nuclear factor-kappa B (NF-kappa B) activation, as well as IFN-gamma induced signal transducer and activator of transcription 1 ( STAT1 ) phosphorylation, were reduced by lovastatin
Ma et al., Mol Pharmacol 2003 : Analyses of the NF-kappaB activation pathway revealed that the antioxidants do not inhibit LPS induced activation of the IkappaB kinase activity, degradation of IkappaBalpha, or translocation of activated NF-kappaB into the nucleus, but they do block the formation of NF-kappaB/DNA binding complexes
Kim et al., Immunology 2005 : Moreover, in vitro kinase assays show that luteolin directly inhibits LPS induced IkappaB kinase (IKK) activity in IEC-18 cells
Yanaka et al., Int J Mol Med 2005 : Although vitamin B6 did not affect cellular proteasome activity, in vitro phosphorylation analysis with glutathione S-transferase fused IkappaBalpha has shown that vitamin B6 suppressed LPS induced IkappaB kinase activation
von Bülow et al., J Immunol 2007 (MAP Kinase Signaling System) : By this mechanism, zinc suppressed LPS induced activation of IkappaB kinase beta (IKKbeta) and NF-kappaB, and subsequent TNF-alpha production