Gene interactions and pathways from curated databases and text-mining

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CSF3 — IRF6

Text-mined interactions from Literome

Hannen et al., Scand J Immunol 1999 : In PBMC, LPS significantly induced G-CSF and interleukin (IL)-1, an inducer of G-CSF
Dembinski et al., Cytokine 2003 (Inflammation) : LPS stimulated maximum levels of IL-6, IL-1beta, TNFalpha and G-CSF in CBC were significantly lower in very preterm infants compared to more advanced gestational age groups
Hareng et al., Eur J Immunol 2003 : In the presence of dibutyryl-cAMP, forskolin, tolafentrine or 3-isobutyl-1-methylxanthine, LPS induced G-CSF formation was enhanced in THP-1 cells, primary monocytes and whole blood ... Correspondingly, rp-8-bromo-cAMP suppressed LPS induced G-CSF release ... Reporter gene studies showed that dibutyryl-cAMP enhanced LPS induced G-CSF promoter activity, indicating a transcriptional up-regulation
Nishizawa et al., FEBS Lett 1992 : The gene expression of granulocyte colony stimulating factor ( G-CSF ) is induced by lipopolysaccharide (LPS)
Lee et al., J Leukoc Biol 1990 : Other events in 1 d-cultured monocytes block the ability to induce G-CSF and GM-CSF expression with LPS , and block the suppressive effect of PGE-2 on M-CSF expression at the RNA level
Nishizawa et al., Mol Cell Biol 1990 : Analyses of linker scanning and internal deletion mutants of the G-CSF promoter by the chloramphenicol acetyltransferase assay have indicated that at least three regulatory elements are indispensable for the LPS induced expression of the G-CSF gene in macrophages
Lu et al., Invest Ophthalmol Vis Sci 2006 : Triptolide and dexamethasone each inhibited in a concentration dependent manner the LPS induced release of IL-6, G-CSF , MCP-1, and IL-8 by corneal fibroblasts ... Whereas the inhibitory effect of dexamethasone on LPS induced IL-6 release was greater than that of triptolide, the inhibitory effect of triptolide on LPS induced G-CSF release was more pronounced than was that of dexamethasone
Nishizawa et al., FEBS Lett 1991 : Granulocyte colony stimulating factor ( G-CSF ) is produced from macrophages in response to lipopolysaccharide (LPS)
Ohki et al., Growth Factors 1991 (Adenocarcinoma...) : The G-CSF promoter was activated by stimulation with LPS , in BAM3 cells, but was inert in RAG cells
Zhou et al., Inflamm Res 2007 : ( 2 ) LXA ( 4 ) decreased LPS induced G-CSF gene expression and protein secretion
Li et al., Neurosci Lett 2009 : It is known that lipopolysaccharide (LPS) can induce macrophages to produce G-CSF
Yu et al., Pediatr Surg Int 2010 (Neoplasms, Experimental...) : Although the conversion of MTT as an indicator of mitochondrial activity was only slightly and not significantly reduced after CO ( 2 ) incubation, the release of G-CSF induced by LPS was completely blocked during the incubation with 100 % CO ( 2 ) ( P < 0.05 )
Son et al., Rheumatol Int 2010 (Syndrome) : However, upon stimulation with MDP, LPS , and PGN, the cells from the BS patient produced much lower levels of TNF-alpha, IL-10, G-CSF , and IFN-gamma than the normal donor cells
Wang et al., Int J Oncol 1994 : The stimulation of t-RA on LPS mediated G-CSF secretion was dose dependent and was observed at t-RA concentration of as low as 10 ( -10 ) M ... Some other retinoids were also as effective as t-RA, whereas other steroids were either less or not effective or inhibitory on LPS mediated G-CSF secretion
Krikun et al., Am J Reprod Immunol 2012 : Treatment of HEECs with LPS significantly upregulated the secretion of IL-6, IL-8, and G-CSF , and this was prevented by LPS-RS
Watari et al., Stem Cells 1994 : Induction of G-CSF by interleukin 1 (IL-1) and lipopolysaccharide (LPS) was compared using enzyme immunoassay in various kinds of stromal cells ... The production of G-CSF by monocytes was stimulated predominantly by LPS , whereas that by KM-102 cells, endothelial cells, and fibroblasts was induced by IL-1 but much less so by LPS ... IL-1 and LPS stimulated similar levels of G-CSF production by primary bone marrow stromal cells which consisted of various types of cells
de Wit et al., Exp Hematol 1993 : Interferon-gamma enhances the LPS induced G-CSF gene expression in human adherent monocytes, which is regulated at transcriptional and posttranscriptional levels ... Human adherent monocytes were studied with regard to the expression of granulocyte colony stimulating factor ( G-CSF ) at mRNA and protein levels in response to lipopolysaccharide (LPS) and gamma-interferon ( IFN-gamma ) stimulation ... The augmented G-CSF mRNA expression in response to IFN-gamma plus LPS was the result of a slight increase in the G-CSF transcription rate ( 2.2-fold ) and a more than 6-fold increase in the G-CSF mRNA half-life ( 20 minutes vs. > 120 minutes ) ... In addition, it was shown that the effects of IFN-gamma on LPS induced G-CSF protein secretion could be mimicked by the calcium ionophore A23187, suggesting that the Ca ( 2+ ) -dependent pathway might be triggered after binding of the ligand to the receptor ... Finally, it was observed that the potentiating effects of IFN-gamma on LPS induced G-CSF secretion could be blocked by interleukin-4 (IL-4)
Inoue et al., Nihon Ronen Igakkai Zasshi 1993 (Disease Susceptibility...) : To clarify the host defence mechanism in the elderly, we studied the effect of recombinant human granulocyte colony stimulating factor ( rhG-CSF ) on neutrophil functions, the production of G-CSF by peripheral blood monocytes in response to lipopolysaccharide (LPS) and the serum levels of G-CSF in patients with bacterial pneumonia
Aman et al., Blood 1994 : Production of granulocyte-macrophage colony stimulating factor ( GM-CSF ), granulocyte-CSF (G-CSF) , and interleukin-1 beta (IL-1 beta) in stromal cell layers was induced by incubation with IL-1 alpha, tumor necrosis factor (TNF), or lipopolysaccharide (LPS)
Svinarich et al., Am J Reprod Immunol 1996 : This study characterizes the LPS induction of G-CSF and RANTES in a first trimester trophoblast cell line
Koyama et al., Am J Physiol 1998 : The release of G-CSF in response to TNF-alpha, LPS , and BK was significantly increased