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IL12B — MNAT1
Text-mined interactions from Literome
Vaidyanathan et al., Cytokine 2001
:
Despite comparable levels of total p35 mRNA, LPS induced
p35 exon 1 transcripts
led to significantly more bioactive
IL-12 from SAC than IFN-gamma/CD40 induced exon 1a/exon 2 transcripts as measured by ELISA
Liu et al., J Exp Med 2003
:
We demonstrate that the levels of
IL-12 p35 protein stimulated by IFN-gamma and lipopolysaccharide (LPS) correspond to those of its mRNA, and that the nuclear factor kappaB signaling pathway is
essential for the induction of IL-12
p35 transcription by LPS
Hayes et al., Blood 1995
:
These results indicated that both p40 and p35 are LPS-inducible in monocytes following IFN-gamma pretreatment, and that the regulated expression of
p35 controls the level of active
IL-12 protein in purified human monocytes