Kowalski-Chauvel et al., J Biol Chem 1996
:
Gastrin stimulates tyrosine phosphorylation of insulin receptor substrate 1 and its association with Grb2 and the phosphatidylinositol 3-kinase ... We report here that Grb2 also interacts with tyrosine phosphorylated IRS-1 in response to gastrin Höcker et al., J Biol Chem 1997
(Stomach Neoplasms) :
Furthermore, whereas gastrin stimulated phosphorylation of Shc proteins and association with Grb2 , activation of the HDC promoter was not influenced by expression of dominant negative Ras ( N15 or N17 ) proteins