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FOS — NOX4

Text-mined interactions from Literome

Chou et al., Toxicol Appl Pharmacol 2002 : Western data showed that NOx increased the expressions of c-Fos , c-Jun, and signaling kinases including MEKK1, JNK1, and p38 ( with induction fold of 3.3, 2.8, and 3.2, respectively ) in the cells 12 h after treatment
Yamagishi et al., J Cardiovasc Pharmacol 2004 : These results demonstrated that azelnidipine inhibited TNF-alpha induced IL-8 expression in HUVEC by blocking NADPH oxidase mediated ROS generation and subsequent AP-1 activation
Shiner et al., Free Radic Biol Med 2004 : The present study demonstrates, for the first time, that PON2 expression increases in monocytes during their maturation into macrophage as a result of NADPH-oxidase activation, and this process is partly regulated by the transcription factor AP-1
Ranjan et al., Antioxid Redox Signal 2006 : Diphenylene iodonium, an inhibitor of NADPH oxidase activity, did not affect dosedependent responses of ERK1/2 or Akt to serum, but markedly inhibited the sequential expression of c-Fos and Fra-1 required for induction of cyclin D1 during cell cycle re-entry ... These results indicate that Nox1 stimulates cell proliferation in actively cycling cells by reducing the requirement for growth factors to maintain expression of cyclin D1, whereas during cell cycle re-entry, NADPH oxidase activity is required for transcriptional activation of Fos family genes during the immediate early gene response
Becskei et al., J Neuroendocrinol 2008 (Synaptic Transmission) : Furthermore, NOX-B11-3 ( 15 mg/kg i.p. ) potently suppressed ghrelin induced ( 25 microg/kg s.c., 12 h after SPM injection ) c-Fos expression in the Arc
Vendrov et al., J Biol Chem 2010 (Atherosclerosis) : Thrombin induced CD44 expression is mediated by transcription factor AP-1 in a NADPH oxidase dependent manner
Hsieh et al., Journal of neuroinflammation 2012 : These results demonstrated that in RBA-1 cells, activation of ATF2/AP-1 by the PKC ( a ) -mediated Nox ( 2 ) /ROS signals is essential for upregulation of MMP-9 and cell migration enhanced by LTA
Lin et al., Cell communication and signaling : CCS 2012 : These results demonstrated that in RBA-1 cells, activation of AP-1 ( c-Fos/c-Jun ) by the PKC-a mediated Nox2/ROS signals is essential for up-regulation of MMP-9 and cell migration enhanced by BK