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FOS — MECOM

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

• IRef Dip Interaction: Complex of JUNB-MECOM-FOS (anti bait coimmunoprecipitation) Bard-Chapeau et al., Proc Natl Acad Sci U S A 2012
• IRef Dip Interaction: Complex of FOS-JUN-MECOM (anti bait coimmunoprecipitation) Bard-Chapeau et al., Proc Natl Acad Sci U S A 2012
• IRef Dip Interaction: Complex of JUN-FOSB-MECOM-JUNB-YY1-FOS-FOSL2 (anti bait coimmunoprecipitation) Bard-Chapeau et al., Proc Natl Acad Sci U S A 2012
• IRef Dip Interaction: FOS — MECOM (physical association, anti bait coimmunoprecipitation) Bard-Chapeau et al., Proc Natl Acad Sci U S A 2012

Text-mined interactions from Literome

Mitani et al., Oncogene 2004 (Leukemia) : Lastly, AML1/EVI-1 enhances AP-1 activity by activating the c-Fos promoter depending on the second zinc-finger domain of EVI-1, and promotes cell proliferation
Dutta et al., Mol Oncol 2013 : While wild type EVI1 efficiently repressed TGFß mediated AP-1 ( activator protein-1 ) and plasminogen activator inhibitor-1 ( PAI-1 ) promoters, EVI1 ( Del190-515 ) elicited a slight increase in both promoter activities
Kurokawa et al., Oncogene 1995 (Cell Transformation, Neoplastic...) : We showed that the transforming effect is correlated with the AP-1 activation induced by AML1/Evi-1
Tanaka et al., Mol Cell Biol 1995 (Cell Transformation, Neoplastic...) : Furthermore, AML1/Evi-1 stimulated c-fos promoter transactivation and increased AP-1 activity, as Evi-1 ( which is not normally expressed in hemopoietic cells ) did