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EPHB2 — SKP1

Text-mined interactions from Literome

Bayle et al., J Biol Chem 2004 : SOCS6 reduced SCF induced activation of ERK1/2 and p38 but not activation of AKT or STATs in Ba/F3, murine embryonic fibroblast (MEF), or COS-7 cells
Tsang et al., J Leukoc Biol 2005 (Inflammation...) : Results indicated that SCF activated ERK , and TNF-alpha activated the p38 MAPK and NF-kappaB pathway ... Therefore, SCF and TNF-alpha acted through ERK and the NF-kappaB pathway to regulate the ICAM-1 expression and elicited the synergistic effect
Khanzada et al., Oncogene 2006 (Carcinoma, Small Cell...) : These responses correlated with the inhibition of stem cell factor (SCF) stimulated activation of extracellular signal regulated kinase ( Erk ), protein kinase B (PKB) and ribosomal S6 kinase by simvastatin
Wong et al., Allergy 2006 : The induction of RANTES by SCF or TNF-alpha was mediated by ERK and NF-kappaB, respectively, and SCF induced MIP-1beta release was mediated by ERK
Suyama et al., Oncol Rep 2010 (Lung Neoplasms...) : Using c-kit positive SCLC cells ( H209 and H69 cells ) and SCF as a model of the autocrine mechanisms, the effects of SCF , LY294002, PD98059 or STI571 on Akt and Erk were assessed by Western blot analysis
Rådinger et al., J Immunol 2011 : The decrease in stem cell factor (SCF) mediated survival in the GSK3ß knockdown HuMCs was reflected by enhancement of SCF withdrawal induced apoptosis, as determined by Annexin V staining and caspase cleavage, and this was associated with a pronounced reduction in SCF mediated phosphorylation of Src homology 2 domain containing phosphatase 2 and ERK1/2 and reduced expression of the antiapoptotic proteins Bcl-xl and Bcl-2
Nakajima et al., J Nat Med 2012 : Signaling analysis with immunoblots revealed that in human melanocytes or human melanoma cells treated with WSE, there was a marked deficiency in SCF stimulated phosphorylation of ERK , MITF and CREB, but not of Raf-1 and MEK