Gene interactions and pathways from curated databases and text-mining

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CDH1 — DNMT1

Text-mined interactions from Literome

Ghoshal et al., Mol Cell Biol 2005 : In contrast, the depletion of Cdh1 with small interfering RNA increased the basal level of DNMT1 that blocked 5-aza-CdR induced degradation
Lakshmikuttyamma et al., Oncogene 2010 (Leukemia, Myeloid, Acute) : In support of this model, we found in acute myeloid leukemia cells with hypermethylated p15INK4B and E-cadherin promoters that the DNMT inhibitor, 5-aza-2'-deoxycytidine, induced p15INK4B and E-cadherin expression, and decreased levels of DNA methylation, histone H3 lysine 9 ( H3K9 ) methylation and SUV39H1 associated with p15INK4B and E-cadherin promoters
Espada et al., Nucleic Acids Res 2011 : Present evidence suggests that the DNMT1 acts on E-cadherin expression through its direct interaction with the E-cadherin transcriptional repressor SNAIL1
Peng et al., Mol Cell Biol 2011 : Finally, inhibition of SIRT1 strengthens the silencing effects of DNMT1 on the expression of tumor suppressor genes ER-a and CDH1 in MDA-MB-231 breast cancer cells
Yi et al., Chemotherapy 2012 (Carcinoma...) : DNMT inhibitors and HDAC inhibitors regulate E-cadherin and Bcl-2 expression in endometrial carcinoma in vitro and in vivo