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CASP8 — UPK3B

Text-mined interactions from Literome

Igaki et al., Proc Natl Acad Sci U S A 2000 : This Drob-1 induced cell death, however, could not be antagonized by baculovirus p35 , a broad-spectrum caspase inhibitor
Shibata et al., J Clin Invest 2000 (Brain Ischemia) : Using the Cre/loxP system, we have established a transgenic mouse line that selectively expresses p35 , a broad-spectrum caspase inhibitor , in OLGs ... Expression of p35 or elimination of caspase-11 suppressed the caspase-3 activation and conferred significant protection against hypoxic injury
Xu et al., Brain Res 2001 : Overexpression of p35 , a general caspase inhibitor , also protected PC12 cells from apoptosis
Moretti et al., Proc Natl Acad Sci U S A 2002 : Adenoviral gene transfer of the caspase inhibitor p35 in vivo prevented caspase-3 activation and vMLC1 cleavage, with positive impact on contractility
Fraser et al., EMBO J 1997 : Caspases are implicated in the execution of apoptosis in Drosophila melanogaster by the observation that expression of baculovirus p35 , a caspase inhibitor , blocks cell death in vivo in Drosophila
Zhou et al., Biochemistry 1998 : We have verified this hypothesis by demonstrating that purified recombinant p35 inhibits human caspase-1 , -3, -6, -7, -8, and -10 with kass values from 1.2 x 10 ( 3 ) to 7 x 10 ( 5 ) ( M-1 s-1 ), and with upper limits of Ki values from 0.1 to 9 nM
Okuno et al., J Biol Chem 1998 (Adrenal Gland Neoplasms...) : In addition, cell death was not inhibited by peptide caspase inhibitors or by expression of p35 , a baculovirus encoded caspase inhibitor , indicating that NO-induced cell death was independent of caspases
Izquierdo et al., EMBO J 1999 : We have produced transgenic mice expressing baculovirus p35 , a broad-range caspase inhibitor