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BMP2 — LEF1

Text-mined interactions from Literome

Hoeppner et al., J Cell Physiol 2009 : BMP2 stimulated Lef1DeltaN expression, whereas Wnt3a blocked basal and BMP2 induced expression of Lef1DeltaN transcripts during osteoblast differentiation
Choe et al., J Neurosci 2013 : We tested the hypothesis that Bmp signaling regulates dentate development in part by controlling the expression of Lef1 , a Wnt responsive transcription factor expressed in dentate stem cells and absolutely required for dentate granule cell production ... Bmp activation through the Acvr1 receptor induced Lef1 expression and neurogenesis in the embryonic DG ... These results suggest that Acvr1 mediated meningeal Bmp signaling regulates Lef1 expression in the dentate, regulating embryonic DG neurogenesis, DG neural stem cell niche formation, and maintenance
Dassule et al., Dev Biol 1998 : Interestingly, both Bmp and Wnt signaling activate Lef1 , making it a candidate for integrating the two distinct signaling pathways