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TP53 — ULK1

Text-mined interactions from Literome

Yin et al., Proc Natl Acad Sci U S A 2004 : p53 mediates checkpoint control at G(1) by transcriptional regulation of p21
Gao et al., Cell Death Differ 2011 : Upregulation of human autophagy-initiation kinase ULK1 by tumor suppressor p53 contributes to DNA-damage induced cell death ... The upregulation of ULK1 ( ULK2 ) /ATG13 complex by p53 is necessary for the sustained autophagy activity induced by DNA damage
Yuan et al., Carcinogenesis 1995 : Our results are consistent with a p53 induced cell cycle block at G1 allowing cells to repair chromosomal damage before DNA replication
Sands et al., Proc Natl Acad Sci U S A 1995 : Mammalian cells that have been treated with agents that damage DNA have an increase in p53 levels, a p53 dependent arrest at G1 in the cell cycle, and a p53 dependent apoptotic response
Nitta et al., Oncogene 1997 : Following the increase in p53 level, cell cycle arrest at G1/S was observed in normal fibroblasts, whereas neither nuclear accumulation of p53 nor cell cycle arrest were observed in HeLa cells
Kushner et al., J Pathol 1997 (Disease Progression...) : p53 regulates cell proliferation and DNA repair by inhibiting the cell cycle at G1/S ; loss of p53 function may therefore lead to aberrant cell kinetics