Gene interactions and pathways from curated databases and text-mining

◀ Back to TP53

DGCR8 — TP53

Pathways - manually collected, often from reviews:

  • NCI Pathway Database Direct p53 effectors: p53 (tetramer)/Drosha/DGCR8/p68 helicase complex (TP53-DROSHA-DDX5-DGCR8) → p53 (tetramer) complex (TP53) (modification, collaborate)
    Suzuki et al., Nature 2009
    Evidence: mutant phenotype, physical interaction
  • NCI Pathway Database Direct p53 effectors: p53 (tetramer)/Drosha/DGCR8/p68 helicase complex (TP53-DROSHA-DDX5-DGCR8) → Drosha/DGCR8/p68 helicase complex (DROSHA-DGCR8-DDX5) (modification, collaborate)
    Suzuki et al., Nature 2009
    Evidence: mutant phenotype, physical interaction
  • NCI Pathway Database Direct p53 effectors: p53 (tetramer) complex (TP53) → Drosha/DGCR8/p68 helicase complex (DROSHA-DGCR8-DDX5) (modification, collaborate)
    Suzuki et al., Nature 2009
    Evidence: mutant phenotype, physical interaction

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *