Gene interactions and pathways from curated databases and text-mining

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RELA — VHL

Text-mined interactions from Literome

An et al., Oncogene 2005 (Carcinoma, Renal Cell...) : Using isogenic paired cell lines with and without expression of wtVHL, we have confirmed that VHL expression reduces constitutive NF-kappaB activity
An et al., Mol Cell Biol 2005 (Kidney Neoplasms) : Recently, VHL loss was shown to activate nuclear factor kappa B (NF-kappaB) , a family of transcription factors that promotes tumor growth
Pantuck et al., Cancer Res 2010 (Carcinoma, Renal Cell...) : Based on earlier evidence that VHL loss can activate NF-kappaB , a known mediator of EMT, we tested whether NF-kappaB contributed to VHL mediated effects on EMT