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RELA — TGFB2
Pathways - manually collected, often from reviews:
Text-mined interactions from Literome
Seppänen et al., Oncol Res 1998
(Adenocarcinoma...) :
In the present study, we have investigated the
effects of interferons-alpha (IFN-alpha) and -gamma ( IFN-gamma ), interleukin-10 (IL-10) and -13 ( IL-13 ),
transforming growth factor-beta1 ( TGF-beta1 ), granulocyte-macrophage colony stimulating factor ( GM-CSF ), and tumor necrosis factor-alpha (TNF-alpha) on cell proliferation and induction of transcription factors AP-1 and
NF-kappaB in UM-EC-3 human endometrial adenocarcinoma cells and UT-OC-5 ovarian carcinoma cells in vitro
Hu et al., J Leukoc Biol 1999
:
Anti-inflammatory cytokines, IL-10, and
transforming growth factor ( TGF ) -beta sequentially
inhibited LPS- and cytokine induced microglial cell
NF-kappaB activation, RANTES mRNA expression, and protein release
Yeung et al., Mol Cell Biol 2001
:
RKIP physically interacted with four kinases of the NF-kappaB activation pathway,
NF-kappaB inducing kinase,
transforming growth factor beta activated kinase 1, IKKalpha, and IKKbeta
Lu et al., Proc Natl Acad Sci U S A 2004
(Neoplasms...) :
Secreted
transforming growth factor beta2 activates
NF-kappaB , blocks apoptosis, and is essential for the survival of some tumor cells
Odabaei et al., Adv Cancer Res 2004
(MAP Kinase Signaling System) :
RKIP has been shown to disrupt the Raf-1-MEK1/2 [ mitogen activated protein kinase-ERK ( extracellular signal regulated kinase ) kinase-1/2 ] -ERK1/2 and NF-kappaB signaling pathways, via physical interaction with Raf-1-MEK1/2 and
NF-kappaB inducing kinase or
transforming growth factor beta activated kinase-1, respectively, thereby abrogating the survival and antiapoptotic properties of these signaling pathways
Mauviel et al., Curr Biol 1993
:
We demonstrate that
transforming growth factor-beta ( TGF-beta ) does not interfere with cytokine induced IL-8 gene expression, nor does it
affect the activity of
NF-kappaB-driven promoters
Neil et al., Cancer Res 2008
(Disease Progression) :
Altered TAB1 :
I kappaB kinase interaction
promotes transforming growth factor beta mediated nuclear factor-kappaB activation during breast cancer progression
Minakawa et al., Biol Pharm Bull 2008
:
In this study, we examined the effect of ISGylation on tumor necrosis factor receptor associated factor ( TRAF)
6/transforming growth factor beta activated kinase ( TAK)-1 dependent
NF-kappaB activation
Miller et al., Mol Cell Biol 1991
:
In 70Z/3 cells,
transforming growth factor beta , an inhibitor of kappa-gene induction,
blocks the upregulation of Oct-2 but not the activation of
NF-kappa B
Cho et al., American journal of physiology. Renal physiology 2009
(Disease Models, Animal...) :
The untreated CKD rats exhibited azotemia, hypertension, hypertriglyceridemia, proteinuria, glomerulosclerosis, tubulointerstitial damage, upregulation of MCP-1, plasminogen activator inhibitor-1 ( PAI-1 ),
transforming growth factor ( TGF ) -beta , cyclooxygenase (COX)-1, COX-2, and NAD ( P ) H oxidase ( NOX-4, gp91(phox), p47(phox) and p22(phox) subunits ) and
activation of
NF-kappaB ( IkappaB phosphorylation )