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RELA — RTKN

Text-mined interactions from Literome

Liu et al., J Biomed Sci 2004 (Adenocarcinoma...) : Our results showed that overexpression of RTKN induced robust activation of NF-kappaB , and RTKN mediated NF-kappaB activation was suppressed significantly by C3 transferase, an inhibitor of the small GTPase Rho ... We conclude that Rho/RTKN mediated NF-kappaB activation leading to cell survival may play a key role in gastric tumorigenesis
Liu et al., Oncogene 2004 : Rho/Rhotekin mediated NF-kappaB activation confers resistance to apoptosis ... Reporter gene assays and electrophoretic mobility shift assay confirmed that RTKN overexpression led to constitutive activation of NF-kappaB through the phosphorylation of IkappaB by IKKbeta