Gene interactions and pathways from curated databases and text-mining

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CR2 — RELA

Text-mined interactions from Literome

D'Addario et al., J Mol Biol 2001 : To our knowledge this is the first report showing that the binding of a herpesvirus envelope glycoprotein to CR2 on human B cells results in the activation of the NF-kappaB transcription factor leading to the upregulation of IL-6 gene expression in these lymphocytes
Tolnay et al., J Immunol 2002 : Here we show that NF-kappaB enhances the expression of the human CR2 gene ... We propose that the NF-kappaB signaling pathway enhances the expression of the CR2 gene, as a result of NF-kappaB proteins binding to two CR2 promoter elements