Gene interactions and pathways from curated databases and text-mining

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PTAFR — PTGS2

Text-mined interactions from Literome

Zhang et al., Exp Dermatol 2006 (Calcium Signaling) : The present study was designed to investigate whether PAF-R activation could induce the expression of COX-2 and production of PGE ( 2 ), as well as secretion of the inflammatory cytokine, interleukin-8 (IL-8), in the immortalized sebaceous gland cell line SZ95
Sahu et al., J Immunol 2013 (Dermatitis, Contact) : In addition, cyclooxygenase-2 inhibition did not block PAF-R agonist production but prevented CS-induced inhibition of CHS
Pei et al., J Immunol 1998 : Activation of the epidermal platelet activating factor receptor results in cytokine and cyclooxygenase-2 biosynthesis ... Studies with the human keratinocyte derived epidermal cell line HaCaT revealed that activation of the endogenous PAF-R led to the increased accumulation of COX-2 , IL-6, and IL-8 mRNA similar to that seen with the KB PAF-R model system