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PI3 — SHC1

Text-mined interactions from Literome

Dominici et al., J Endocrinol 2000 : ects is associated with : ( 1 ) increased IR abundance, ( 2 ) increased insulin stimulated IR tyrosine phosphorylation, ( 3 ) normal efficiency of IRS-1 and Shc tyrosine phosphorylation and ( 4 ) normal activation of PI 3-kinase by insulin
Ugi et al., J Biol Chem 2002 : In support of this, we found that the PI 3-kinase inhibitors, wortmannin and LY294002, blocked insulin stimulated but not EGF- or PDGF stimulated Shc phosphorylation ... Consistent with this, expression of a constitutively active PI 3-kinase ( p110 ( C ) ( AAX ) ) increased membrane localization of Shc , and this was completely blocked by wortmannin
Harrison-Findik et al., Oncogene 1995 (Leukemia, Myelogenous, Chronic, BCR-ABL Positive) : P210 BCR/abl tyrosine kinase induces tyrosine phosphorylation of Shc , and activation of p21ras and PI 3-Kinase
Cerboni et al., Eur J Immunol 1998 : CD16 mediated activation of phosphatidylinositol-3 kinase (PI-3K) in human NK cells involves tyrosine phosphorylation of Cbl and its association with Grb2, Shc , pp36 and p85 PI-3K subunit