Gene interactions and pathways from curated databases and text-mining

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IRF6 — OLR1

Text-mined interactions from Literome

Shibata et al., Atherosclerosis 2007 : Thus, mulberry leaf aqueous fractions suppress TNF-alpha- and LPS induced LOX-1 gene expression, by inhibiting NF-kappaB activation
Dawson et al., J Nutr Biochem 2012 (Hypertriglyceridemia...) : However, LPS did not induce OLR1 mRNA expression
Pang et al., Biochim Biophys Acta 2012 (Inflammation) : We provide novel evidence demonstrating that the anti-inflammatory effects of minocycline in human monocytes include, in addition to decreased NF-?B activation, abrogation of the LPS stimulated LOX-1 , LITAF, Nur77 pathways, p38 MAPK inhibition and PI3K/Akt activation
Wang et al., Experimental biology and medicine (Maywood, N.J.) 2012 (Inflammation) : Like Ang II, LPS increased the expression of AT1R, AT2R and LOX-1 ... The selective inhibitors of MAPKs, c-Jun and NF-?B each blocked the transcription of LOX-1 and pro-inflammatory genes in response to Ang II as well as LPS