◀ Back to IRF6

IRF6 — MSH3

Text-mined interactions from Literome

Gupta et al., Kidney Int 2000 : NOS2 promoter assays were conducted to identify the effects of alpha-MSH on LPS + IFN-gamma mediated induction of NOS2 transcription ... alpha-MSH ( 100 nmol/L ) inhibited the LPS + IFN-gamma mediated induction of nuclear DNA binding activity of C/EBPbeta, but not that of NF-kappaB ( in contrast to reports in other cell types ), as well as the activity of a murine NOS2 promoter-luciferase construct
Cherrington et al., Drug Metab Dispos 2004 : In contrast, LPS increased mRNA levels of Mrp1 , Mrp3, and Mdr1b concurrently with the down-regulated transporters ... Furthermore, dexamethasone pretreatment also prevented the LPS mediated increase in Mrp1 , Mrp3, and Mdr1b, whereas pretreatment with aminoguanidine or gadolinium chloride, an inhibitor of inducible nitric oxide synthetase and a Kupffer cell toxicant, respectively, had no effect on the LPS induced changes
Mastronardi et al., Neuroimmunomodulation 2005 (Bacterial Infections...) : Our results suggest that alpha-MSH increased leptin release without altering its synthesis, but when LPS increased release and synthesis of leptin, alpha-MSH , although further increasing release, blocked the enhanced synthesis of leptin elicited by LPS
Sobel et al., Endocr Res 1990 : Bacterial lipopolysaccharide (LPS) and corticotropin releasing hormone (CRH) plus arginine vasopressin (AVP) induce immunoassayable ( 1-13 ) ACTH ( alpha MSH ) from mononuclear leukocytes
Hwang et al., Fish Shellfish Immunol 2007 : Japanese flounder MSH was observed to be highly expressed in immune related tissues and are induced by immune stimulants, lipopolysaccharide (LPS) , polyI : C and peptidoglycan ( PG ) in vitro suggesting that it is involved in fish immunity particularly against viral and bacterial agents, a functional feature exhibited by previously reported fish cytokines