Gene interactions and pathways from curated databases and text-mining

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IRF6 — KLF4

Text-mined interactions from Literome

Liu et al., Shock 2008 (Inflammation) : Moreover, compared with the control group, the release of HMGB1 was increased after KLF4 overexpression after LPS treatment, whereas the release of HMGB1 was decreased after KLF4 deficiency in response to LPS ... Electrophoretic mobility shift assay results showed the binding of KLF4 to the oligonucleotides designed according to the HMGB1 promoter, and the binding activity was increased in response to LPS stimulation
Kaushik et al., Journal of neuroinflammation 2010 (Encephalitis) : LPS stimulation increased Klf4 expression in microglial cells in a time- and dose dependent manner