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IL4 — MMP3

Text-mined interactions from Literome

Meisser et al., Mol Hum Reprod 1999 : The aim of this study was to determine the effects of tumour necrosis factor alpha (TNF), interleukin-1 alpha (IL-1alpha), macrophage colony stimulating factor ( MCSF ) and transforming growth factor beta ( TGFbeta ) on the secretion of matrix metalloproteinases ( MMP ) , human chorionic gonadotrophin ( HCG ) and fetal fibronectin ( fFN ) by purified first trimester cytotrophoblastic cells (CTB) in vitro
Oriente et al., J Pharmacol Exp Ther 2000 : In KF, IL-13 and IL-4 inhibited MMP-3 , whereas TGF-beta(1) enhanced MMP-3 ; TIMP-1 was unaffected by any of the three cytokines
Lee et al., J Allergy Clin Immunol 2003 (Asthma...) : These results suggest that MMP inhibitors regulate inflammatory cell migration by reducing ICAM-1 and VCAM-1 expression and possibly also by suppressing IL-1beta, IL-4 , and TNF-alpha expression
Bamba et al., J Gastroenterol 2003 : Matrix metalloproteinase-3 secretion from human colonic subepithelial myofibroblasts : role of interleukin-17
Fleenor et al., Invest Ophthalmol Vis Sci 2003 : In the trabecular meshwork ( TM ), interleukin (IL)-1alpha is a potent inducer of MMP-3 expression
Sun et al., Connect Tissue Res 2003 (Arthritis, Rheumatoid) : Furthermore, the induction of the MMP expression and activities by interleukin-1 was suppressed by the oscillatory shear
Borghaei et al., Biochem Biophys Res Commun 2004 : A 5T/6T polymorphic site in the matrix metalloproteinase-3 (MMP-3) promoter has been identified as a repressor element involved in inhibiting induction of MMP-3 transcription by interleukin 1 ; and the 6T allele has been associated with decreased expression of MMP-3 as compared to the 5T allele
Jenkins et al., J Periodontol 2004 (Periodontitis) : The objective of this study is to determine the effects of IL-4 on the IL-1 induced expression of MMP-3 in human gingival fibroblasts isolated from patients with periodontitis ... IL-4 inhibits the IL-1 induction of MMP-3 in human gingival fibroblasts isolated from patients with periodontitis
Inoue et al., Rheumatol Int 2005 (Osteoarthritis, Hip...) : Induction of vascular endothelial growth factor and matrix metalloproteinase-3 ( stromelysin ) by interleukin-1 in human articular chondrocytes and synoviocytes
Yang et al., Arthritis Rheum 2005 (Arthritis, Experimental...) : These data demonstrate the requirement of PAR-1 for the expression of AIA, the development of an antigen-specific Ig response, thrombin induced macrophage cytokine and MMP expression, and the inhibitory effect of PAR-1 on serum IL-4
Fukuda et al., Invest Ophthalmol Vis Sci 2006 : IL-4 and -13 each inhibit MMP-3 synthesis in human conjunctival fibroblasts, suggesting that these Th2 cytokines may contribute to the excessive deposition of ECM in giant papillae by preventing matrix degradation mediated by this enzyme
Stewart et al., BMC molecular biology 2007 : Interleukin-4 inhibition of interleukin-1 induced expression of matrix metalloproteinase-3 (MMP-3) is independent of lipoxygenase and PPARgamma activation in human gingival fibroblasts ... Interleukin-4 inhibition of interleukin-1 induced expression of matrix metalloproteinase-3 (MMP-3) is independent of lipoxygenase and PPARgamma activation in human gingival fibroblasts ... The objective of this study was to determine whether the suppressive effects of IL-4 on the IL-1 induced expression of MMP-3 involve activation of lipoxygenase and/or PPARgamma
Chang et al., Rheumatol Int 2007 (Chondrosarcoma) : Activin A suppresses interleukin-1 induced matrix metalloproteinase 3 secretion in human chondrosarcoma cells
Wang et al., J Biol Chem 2010 : Importance of protein-tyrosine phosphatase-alpha catalytic domains for interactions with SHP-2 and interleukin-1 induced matrix metalloproteinase-3 expression
Gotoh et al., Connect Tissue Res 2013 : Extracellular ß-NAD ( + ) inhibits interleukin-1 induced matrix metalloproteinase-1 and -3 expression on human gingival fibroblasts
Chambers et al., Exp Cell Res 2013 (Periodontitis) : Previous studies showed that IL-4 inhibits induction of MMP-3 by IL-1ß, and suggested that AP-1 might be involved ... These results indicate that IL-4 inhibition of MMP-3 expression is associated with reduction of IL-1 induced binding of active forms of the AP-1 dimer, while less active JunB containing dimers remain, and suggest that these changes are associated with decreased activation of JNK