Gene interactions and pathways from curated databases and text-mining

◀ Back to IL21

IL21 — MMP1

Text-mined interactions from Literome

Meisser et al., Mol Hum Reprod 1999 : The aim of this study was to determine the effects of tumour necrosis factor alpha (TNF), interleukin-1 alpha (IL-1alpha), macrophage colony stimulating factor ( MCSF ) and transforming growth factor beta ( TGFbeta ) on the secretion of matrix metalloproteinases ( MMP ) , human chorionic gonadotrophin ( HCG ) and fetal fibronectin ( fFN ) by purified first trimester cytotrophoblastic cells (CTB) in vitro
Ray et al., Arthritis Rheum 2003 (Osteoarthritis) : Overexpression of SAF-1 in OA chondrocytes increased the expression of the MMP1 promoter, and interference of endogenous SAF-1 activity by antisense SAF-1 messenger RNA inhibited interleukin-1 mediated MMP1 promoter activity
Sun et al., Connect Tissue Res 2003 (Arthritis, Rheumatoid) : Furthermore, the induction of the MMP expression and activities by interleukin-1 was suppressed by the oscillatory shear
Monteleone et al., Gut 2006 (Colitis, Ulcerative...) : To investigate whether IL21 controls MMP production by intestinal fibroblasts ... IL21 enhances fibroblast production of MMP-1, MMP-2 , MMP-3 and MMP-9, but not tissue inhibitors of MMP-1 and MMP-2 ... IL21 enhances fibroblast production of MMP-1 , MMP-2, MMP-3 and MMP-9, but not tissue inhibitors of MMP-1 and MMP-2 ... IL21 enhances MMP secretion without affecting gene transcription and protein synthesis ... These results suggest that fibroblasts are a potential target of IL21 in the gut and that IL21 controls MMP secretion by fibroblasts
Caruso et al., J Immunol 2007 (Gastritis...) : In this study, we have examined the role of the T cell cytokine IL-21 in Hp-infected gastric mucosa and evaluated whether IL-21 regulates MMP production by gastric epithelial cells
Abe et al., J Nat Prod 2010 : The effects of these new compounds on interleukin-1ß induced production of matrix metalloproteinase-1 (MMP-1) in human dermal fibroblasts were examined
Gotoh et al., Connect Tissue Res 2013 : Extracellular ß-NAD ( + ) inhibits interleukin-1 induced matrix metalloproteinase-1 and -3 expression on human gingival fibroblasts
Langdon et al., Arthritis Rheum 1997 (Arthritis, Rheumatoid) : Oncostatin M stimulates monocyte chemoattractant protein-1- and interleukin-1 induced matrix metalloproteinase-1 production by human synovial fibroblasts in vitro
Dean et al., J Biol Chem 1999 : We have previously shown that the pyridinyl imidazole SB 203580, which inhibits it, blocks the interleukin-1 induction of cyclooxygenase-2 (COX-2) and matrix metalloproteinase 1 and 3 mRNAs in fibroblasts