Gene interactions and pathways from curated databases and text-mining

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IL2 — ZEB1

Text-mined interactions from Literome

Wang et al., Int Immunol 2009 : Over-expression of ZEB1 can repress IL-2 promoter activity, as well as endogenous IL-2 mRNA production in EL-4 T cells, and this repression is dependent on the ZEB binding site at -100
Yasui et al., J Immunol 1998 : Transcriptional repression of the IL-2 gene in Th cells by ZEB ... We provide evidence that repression of IL-2 gene expression in Th2 cells and partial repression in Th1 cells are mediated by ZEB , a zinc finger, E box binding transcription factor