Gene interactions and pathways from curated databases and text-mining

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EPHB2 — RAB1A

Text-mined interactions from Literome

Wu et al., J Biol Chem 2003 : Similarly, expression of dominant negative Rab1 mutants and siRNA depletion of Rab1 significantly attenuated AT1R mediated inositol phosphate accumulation and ERK1/2 activation and beta2-AR mediated ERK1/2 activation, but not alpha2B-AR stimulated ERK1/2 activation
Filipeanu et al., Mol Pharmacol 2006 (MAP Kinase Signaling System) : Consistent with the effects on receptor cell-surface targeting, Rab1 selectively enhanced ERK1/2 activation and hypertrophic growth in response to the alpha1-AR agonist phenylephrine but not to the beta-AR agonist isoproterenol ... Rab1N124I inhibited both agonist mediated ERK1/2 activation and hypertrophic growth in neonatal myocytes