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EPHB2 — RAB1A
Text-mined interactions from Literome
Wu et al., J Biol Chem 2003
:
Similarly, expression of dominant negative
Rab1 mutants and siRNA depletion of Rab1 significantly
attenuated AT1R mediated inositol phosphate accumulation and
ERK1/2 activation and beta2-AR mediated ERK1/2 activation, but not alpha2B-AR stimulated ERK1/2 activation
Filipeanu et al., Mol Pharmacol 2006
(MAP Kinase Signaling System) :
Consistent with the effects on receptor cell-surface targeting,
Rab1 selectively
enhanced ERK1/2 activation and hypertrophic growth in response to the alpha1-AR agonist phenylephrine but not to the beta-AR agonist isoproterenol ...
Rab1N124I inhibited both agonist mediated
ERK1/2 activation and hypertrophic growth in neonatal myocytes