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EPHB2 — MAP3K3
Text-mined interactions from Literome
Adams et al., Arch Biochem Biophys 2002
:
However, neither of these phosphorylated amino acids is required for association with 14-3-3 protein or regulation of
MEKK3 dependent
ERK and JNK activity
Xu et al., J Biol Chem 2004
:
Expression of dominant negative mutants of MEKK2 and
MEKK3 also
blocked activation of
ERK5 by WNK1
Fritz et al., J Biol Chem 2006
:
MEKK3 dependent
activation of an NF-kappaB reporter gene as well as
ERK , JNK, and p38 MAP kinases correlated with a requirement for serine at position 526
Wang et al., J Biol Chem 2006
:
Our evidence also indicates that Ras and
MEKK3 , a MEK5 kinase in non-neuronal cells, do not
play a significant role in BDNF activation of
ERK5
Deng et al., Am J Physiol Cell Physiol 2007
(Neoplasms, Experimental...) :
We also found that
MEKK3 is
required for angiopoietin-1 (Ang1) induced p38 and
ERK5 activation
Hebron et al., Br J Haematol 2013
(Multiple Myeloma...) :
In myeloma tumour cells,
MAP3K8 acts as mitogen induced MAP3K in mitosis and is
required for TNFa mediated
ERK activation