Gene interactions and pathways from curated databases and text-mining

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IRF6 — SLC2A1

Text-mined interactions from Literome

Fu et al., Blood Cells Mol Dis 2004 : Monocytes expressed 8.4-fold more GLUT 3 protein and 88 % less GLUT 1 than lymphocytes, and activation by lipopolysaccharide (LPS) led to a 1.9-fold increase in GLUT 1
Schuster et al., Am J Physiol Lung Cell Mol Physiol 2007 : LPS stimulation did not increase GLUT-1 protein levels but did cause translocation of GLUT-1 from the cell interior to the cell surface, together with a dose dependent increase in [ 3H ] DG uptake, indicating that glucose uptake is regulated in these cells
Cao et al., J Nutr 2008 (Inflammation) : CPE and LPS increased GLUT1 expression ( the major GLUT form in macrophages ) to 3- and 2-fold that of the control, respectively