Zhang et al., Cancer Lett 2008
(Carcinoma, Hepatocellular...) :
Researches have shown that ING2 can activate p53 and p53 mediated apoptotic pathway involved in the hepatocarcinogenesis
Madapura et al., Cell cycle (Georgetown, Tex.) 2012
:
Modifying p53 levels using Nutlin-3, which specifically dissociates the MDM2-p53 interaction, was sufficient to upregulate SAP expression, indicating that SAP is a target of p53 in T cells