◀ Back to TP53
ROCK2 — TP53
Pathways - manually collected, often from reviews:
Text-mined interactions from Literome
Qin et al., J Neurosci 2009
:
p53 inhibition induced axonal growth cone collapse was significantly
reduced by the Rho kinase (
ROCK ) inhibitor, Y27632 [ ( R ) - ( + ) -trans-N- ( 4-pyridyl ) -4- ( 1-aminoethyl ) -cyclohexanecarboxamide ]
Qin et al., PloS one 2010
(Niemann-Pick Disease, Type C) :
Finally, in vivo
ROCK inhibition significantly
increased phosphorylated
p53 levels and neurofilaments in axons, and axonal bundle size in npc1-/- mice