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MAP4 — TP53

Text-mined interactions from Literome

Zhang et al., Cancer Res 1999 : DNA damage increases sensitivity to vinca alkaloids and decreases sensitivity to taxanes through p53 dependent repression of microtubule associated protein 4 ... Expression of MAP4 is transcriptionally repressed by wild-type p53
Chao et al., EMBO J 2000 : p53 ( Gln25Ser26 ) was stable but did not accumulate after DNA damage ; the expression of p21/Waf1 and PERP was not induced, and p53 dependent repression of MAP4 expression was abolished
Bash-Babula et al., Clin Cancer Res 2002 (Anemia...) : We reported that wild-type p53 induction by doxorubicin in C127 breast cancer cells repressed MAP4 , decreased microtubule polymerization, and increased Vinca alkaloid sensitivity
Murphy et al., Genes Dev 1996 : Wild-type p53 negatively regulates the expression of a microtubule associated protein