Gene interactions and pathways from curated databases and text-mining

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ESR2 — SLC22A3

Text-mined interactions from Literome

Park et al., Mol Endocrinol 2008 (Ovarian Neoplasms) : We also showed that ERbeta had an opposing action on ERalpha because the presence of ERbeta completely inhibited the EMT and down-regulation of E-cadherin induced by ERalpha
Mak et al., Cancer Cell 2010 (Prostatic Neoplasms) : Stimuli ( TGF-beta and hypoxia ) that induce an epithelial-mesenchymal transition (EMT) diminish ERbeta expression, and loss of ERbeta is sufficient to promote an EMT