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SGK1 — TRPV5
Text-mined interactions from Literome
Embark et al., Cell Physiol Biochem 2004
:
The present study aims to explore whether
TRPV5 is
regulated by the serum and glucocorticoid inducible kinase
SGK1 , a kinase transcriptionally upregulated by 1,25 ( OH ) 2D3 ... The
effect of ( S422D )
SGK1 on
TRPV5 and NHERF2 expressing oocytes is mimicked by SGK1 and SGK3, but not by SGK2, constitutively active ( T308D, S473D ) PKB or inactive ( K127N ) SGK1 ... The observations suggest that
SGK1 , SGK3 and NHERF2
regulate TRPV5 and are thus likely to participate in the regulation of calcium homeostasis
Palmada et al., Cell Physiol Biochem 2005
:
Requirement of PDZ domains for the stimulation of the epithelial Ca2+ channel
TRPV5 by the NHE
regulating factor NHERF2 and the serum and glucocorticoid inducible kinase
SGK1 ... As shown recently,
TRPV5 is
activated by the serum and glucocorticoid inducible kinase
SGK1 , a kinase transcriptionally upregulated by 1,25 ( OH ) 2D3