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NTRK1 — RAC1
Pathways - manually collected, often from reviews:
Text-mined interactions from Literome
Dey et al., Exp Cell Res 2005
:
These data suggest a distinct requirement for CSK in the regulation of
NGF/TrkA activation of RAS,
RAC , ERK, and AKT via the differential control of SFKs in the orchestration of neuronal differentiation
Wang et al., Biochem Soc Trans 2006
(Second Messenger Systems) :
This represents the first example of a
Rac-GAP regulated directly by DAG in
response to the activation of a
tyrosine kinase receptor , and suggests a previously unappreciated role for this lipid as a negative modulator of Rac signalling