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KRAS — RAC1

Pathways - manually collected, often from reviews:

• NCI Pathway Database Neurotrophic factor-mediated Trk receptor signaling: RAC1/GDP complex (RAC1) → RAS family/GTP/Tiam1 complex (HRAS_KRAS_HRAS_KRAS_NRAS-TIAM1) (modification, collaborate)
  Yamauchi et al., Proc Natl Acad Sci U S A 2005
  Evidence: assay, other species
• NCI Pathway Database Neurotrophic factor-mediated Trk receptor signaling: RAS family/GTP/Tiam1 complex (HRAS_KRAS_HRAS_KRAS_NRAS-TIAM1) → RAC1/GTP complex (RAC1) (modification, activates) Yamauchi et al., Proc Natl Acad Sci U S A 2005
  Evidence: assay, other species

Text-mined interactions from Literome

Walsh et al., J Biol Chem 2001 : These results suggest that K-Ras activates Rac more efficiently than Ha-Ras ... The preferential activation of Rac by K-Ras is dependent on the mode of membrane anchoring and impacts on the ability of K-Ras to regulate cell survival
Dreissigacker et al., Cell Signal 2006 (Neoplasm Invasiveness...) : Stable expression of EGFP-K-Ras ( V12 ) down-regulated the activity of Rac1 and RhoA, resulting in reduced subcortical actin filaments and stress fibers, which might contribute to the epithelial dedifferentiation