Gene interactions and pathways from curated databases and text-mining

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EZR — RAC1

Text-mined interactions from Literome

Auvinen et al., Exp Cell Res 2007 : We suggest that localization of ezrin in adherens junctions is regulated by Rac in a manner involving PIPK
Rossy et al., Exp Cell Res 2007 (Carcinoma 256, Walker) : We further show that endogenous ezrin and moesin are phosphorylated and that activities of PI-3 kinase, Rho and Rac , but not of Rho-kinase, are required for this C-terminal phosphorylation
Ruan et al., Mol Biol Cell 2008 : Our results define a new domain, topologically and functionally distinct from the death domain, which regulates neuritogenesis via recruitment of ezrin and activation of Rac1