Gene interactions and pathways from curated databases and text-mining

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NFKBIA — PRKAR1B

Text-mined interactions from Literome

Takahashi et al., Eur J Biochem 2002 (MAP Kinase Signaling System) : PKA activators affected neither IkappaBalpha phosphorylation, IkappaBetaalpha degradation, nor the NF-kappaBeta/DNA binding
Kobayashi et al., J Biol Chem 2005 : RANKL induced degradation of I kappa B alpha and phosphorylation of p38 MAPK and c-Jun N-terminal kinase in RAW264.7 cells were up-regulated by PGE2 in a cAMP dependent protein kinase A (PKA) dependent manner, suggesting that EP2 and EP4 signals cross-talk with RANK signals