◀ Back to MAP3K7
MAP3K7 — TAB3
Pathways - manually collected, often from reviews:
-
KEGG NOD-like receptor signaling pathway:
RIPK2
→
Complex of MAP3K7-TAB1-TAB2-TAB3
(protein-protein, activation)
-
KEGG NOD-like receptor signaling pathway:
Complex of MAP3K7-TAB1-TAB2-TAB3
→
Complex of CHUK-IKBKB-IKBKG
(protein-protein, activation)
-
KEGG NOD-like receptor signaling pathway:
Complex of MAP3K7-TAB1-TAB2-TAB3
→
MAPK1/MAPK3
(protein-protein, activation)
-
KEGG NOD-like receptor signaling pathway:
Complex of MAP3K7-TAB1-TAB2-TAB3
→
MAPK10/MAPK8/MAPK9
(protein-protein, activation)
-
KEGG NOD-like receptor signaling pathway:
Complex of MAP3K7-TAB1-TAB2-TAB3
→
MAPK11/MAPK12/MAPK13/MAPK14
(protein-protein, activation)
-
Reactome Reaction:
MAP3K7
→
TAB3
(reaction)
Kishimoto et al., J Biol Chem 2000, Sakurai et al., FEBS Lett 2000, Ono et al., J Biol Chem 2001, Sato et al., Nat Immunol 2005, Shim et al., Genes Dev 2005, Brown et al., J Mol Biol 2005, Adhikari et al., Oncogene 2007, Shibuya et al., Science 1996
-
Reactome Reaction:
MAP3K7
→
TAB3
(direct_complex)
Kishimoto et al., J Biol Chem 2000, Sakurai et al., FEBS Lett 2000, Ono et al., J Biol Chem 2001, Sato et al., Nat Immunol 2005, Shim et al., Genes Dev 2005, Brown et al., J Mol Biol 2005, Adhikari et al., Oncogene 2007, Shibuya et al., Science 1996
Protein-Protein interactions - manually collected from original source literature:
Studies that report less than 10 interactions are marked with *
-
IRef Biogrid Interaction:
TAB3
—
MAP3K7
(physical association, affinity chromatography technology)
Criollo et al., EMBO J 2011
-
IRef Biogrid Interaction:
TAB3
—
MAP3K7
(direct interaction, pull down)
Mendoza et al., Biochem J 2008*
-
IRef Biogrid Interaction:
TAB3
—
MAP3K7
(physical association, affinity chromatography technology)
Hong et al., Nat Immunol 2007
-
IRef Biogrid Interaction:
TAB3
—
MAP3K7
(physical association, affinity chromatography technology)
Minoda et al., Biochem Biophys Res Commun 2009*
-
IRef Biogrid Interaction:
TAB3
—
MAP3K7
(physical association, affinity chromatography technology)
Cheung et al., Biochem J 2004*
-
IRef Biogrid Interaction:
TAB3
—
MAP3K7
(physical association, affinity chromatography technology)
Ishitani et al., EMBO J 2003
-
IRef Biogrid Interaction:
TAB3
—
MAP3K7
(physical association, affinity chromatography technology)
Li et al., Immunity 2011
-
MIPS CORUM TNF-alpha/NF-kappa B signaling complex 7:
TNF-alpha/NF-kappa B signaling complex 7 complex (CDC37-FKBP5-HSP90AA1-HSP90AB1-MAP3K7-TAB1-TAB2-TAB3)
Bouwmeester et al., Nat Cell Biol 2004
-
IRef Corum Interaction:
Complex of HSP90AA1-MAP3K7-TAB1-CDC37-FKBP5-HSP90AB1-TAB3-TAB2
(association, tandem affinity purification)
Bouwmeester et al., Nat Cell Biol 2004
-
IRef Hprd Interaction:
Complex of 57 proteins
(in vivo)
Bouwmeester et al., Nat Cell Biol 2004
-
IRef Intact Interaction:
Complex of TAB3-TRAF6-MAP3K7
(association, anti tag coimmunoprecipitation)
Jiang et al., J Biol Chem 2003
-
IRef Intact Interaction:
Complex of TAB1-MAP3K7-TAB3-TAB2-TAB3-MAP3K7-TAB2-TAB1
(association, anti tag coimmunoprecipitation)
Li et al., Immunity 2011
-
IRef Intact Interaction:
Complex of BECN1-MAP3K7-TAB3
(association, anti bait coimmunoprecipitation)
Criollo et al., EMBO J 2011
-
IRef Intact Interaction:
TAB3
—
MAP3K7
(physical association, tandem affinity purification)
Bouwmeester et al., Nat Cell Biol 2004
-
IRef Intact Interaction:
TAB3
—
MAP3K7
(physical association, anti bait coimmunoprecipitation)
Criollo et al., EMBO J 2011
-
IRef Ophid Interaction:
TAB3
—
MAP3K7
(aggregation, confirmational text mining)
Bouwmeester et al., Nat Cell Biol 2004
-
IRef Ophid Interaction:
TAB3
—
MAP3K7
(aggregation, interologs mapping)
Brown et al., Bioinformatics 2005
Text-mined interactions from Literome
Cheung et al., Biochem J 2004
:
The SAPK2a/p38alpha mediated phosphorylation of TAB2 and
TAB3 may
contribute to the SAPK2a/p38alpha mediated feedback control of
TAK1 activity that also involves the phosphorylation of TAB1
Besse et al., J Biol Chem 2007
:
TAK1 dependent signaling
requires functional interaction with
TAB2/TAB3
Prickett et al., J Biol Chem 2008
:
TAB4 stimulates
TAK1-TAB1 phosphorylation and binds polyubiquitin to direct signaling to NF-kappaB ... Recombinant
GST-TAB4 bound in an overlay assay directly to inactive TAK1 and
activated TAK1 but not TAK1 phosphorylated in the linker sites, suggesting a bind and release mechanism